Research program

From mechanism to evidence to inference.

Three connected layers examine how computational systems can strengthen clinical inquiry without obscuring uncertainty or replacing human judgment.

I

Mechanistic foundation

Understand physiology

Begin with the mechanisms that support muscle function and movement, expressed through clinically meaningful educational models.

Explore Physiolog
II

Population knowledge

Represent the evidence

Turn literature into curated causal knowledge while preserving provenance, uncertainty, disagreement, and scientific review.

Explore Models4PT
III

Individual reasoning

Ask what follows here

Explore causal models, Bayesian inference, and iterative belief revision for inspectable, patient-specific explanations.

Explore the Inference Engine

Working principles

Epistemic safeguards belong in the architecture.

01

Population knowledge is not a patient conclusion.

General evidence constrains individual reasoning; it does not determine it without patient findings, context, and uncertainty.

02

Association is not causation.

Evidence types, causal claims, concepts, measurements, and curation decisions remain explicit rather than being collapsed into one record.

03

AI output is candidate knowledge.

Extraction can assist scientific work, but ontology resolution and human curation remain necessary before a claim enters the knowledge base.

04

Explanations should remain inspectable.

Inference systems should expose evidence, assumptions, model versions, uncertainty, and reasoning steps to scientific and clinical review.

The boundary

One program, not one monolithic product.

The projects are conceptually and architecturally aligned, but they are not yet technically integrated.

Physiolog is a deployed educational platform. Models4PT is an early research prototype for population-level causal knowledge. The Clinical Inference Engine defines a future patient-specific inference layer. Keeping those boundaries visible is part of the scholarly argument.

See project details

The aim is not to automate clinical judgment. It is to make the knowledge, assumptions, uncertainty, and inferential steps supporting that judgment more explicit.